Hormone Replacement Therapy (HRT, for short) is a method many trans guys undertake to alleviate gender dysphoria. Typically, HRT is comprised of taking synthetic testosterone (colloquially known as "T") in either injections or a topical gel. There are many effects that happen to the body when taking synthetic testosterone, though medical research about T is still in its infancy.

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There is no one or "correct" way to take T. The dosage and application method are entirely up to the individual and their care provider. Below is information consolidated from medical professionals and real trans guys on their experiences taking testosterone. No one at the Trans Guy Archive is a medical professional and nothing on this page should be interpreted as explicit medical advice. If you have serious medical questions, contact your doctor or care provider.